ENYO Pharma Announces completion and topline data from Phase 2 ALPESTRIA-1 clinical study in Alport syndrome demonstrating Vonafexor reverses kidney function decline and has sustained therapeutic benefit
And continued progress of its alpestria-1 clinical phase 2 study in alport syndrome patient Vonafexor reversed a historical mean eGFR decline of -6.4 mL/min/1.73 m²/yr to a mean functional gain on-treatment of +4.8 mL/min/1.73 m²/yr from baseline 73% of patients maintained albuminuria reduction three months after treatment cessation consistent with a true disease-modifying effect Company plans to advance vonafexor to